Welcome to the Biotage Scale Up Blogs.

      How to Remove Palladium in three easy steps

      May 6, 2020 3:37:11 PM / by Sunil Rana posted in Troubleshooting and Optimization, Scale-Up, Scavenger, metal scavenger key article

      0 Comments

       

      Introduction

      Removing palladium has become more and more difficult for a number of reasons.  Industry is using it more frequently, due to its greener credentials as a catalyst but regulatory bodies are also reducing acceptable limits in APIs.  One of the most significant changes for pharma recently has been increased scrutiny of impurities in pharma products.

      Read More

      Practical Lab methods for the development of metal removal processes

      May 6, 2020 3:36:29 PM / by Sunil Rana posted in Scale-Up, Scavenger, metal scavenger key article

      0 Comments

       

      There are two starting points, depending on your preference of whether you want to stir in a batch or flow something though a tube. If you plan to use large scale up reactors, then batch stir methods are great, but if you imagine wanting to flow material through a ‘cleaning’ column, then the SPE quick test works well.

      Read More